PUBLICATIONS AND ARTICLES

  • 2024

Mamis E., et al, Target development towards first production of high molar activity 44gSc and 47Sc by mass separation at CERN-MEDICIS, published in Pharmaceuticals (2024)  https://www.mdpi.com/1424-8247/17/3/390

Van Laere C., Koole M., Deroose C.M., Van de Voorde M., Baete K., Cocolios T.E., Duchemin C., Ooms M., Cleeren F. Terbium radionuclides for theranostic applications in nuclear medicine: from atom to bedside. Theranostics 2024; 14(4): 1720-1743. doi:10.7150/thno.92775

  • 2023

Radzina M, Saule L, Mamis E, Koester U, Cocolios T, Pajuste E, Kalnina M, Palskis K, Sawitzki Z, Talip Z, Jensen M, Duchemin C, Leufgen K, Stora T. Novel radiouclides for use in nuclear medicine in europe: where do we stand and where do we go? https://ejnmmipharmchem.springeropen.com/articles/10.1186/s41181-023-00211-5

Bernerd C., Duchemin C., Khan Q., Lambert L., Mamis E., Rossel R., Stora T. The CERN MEDICIS facility: an update, ISOLDE Newsletter 2023, (2023).

Stora T. et al CERN-MEDICIS: Operational indicators to support the production of new medical radionuclides by mass zseparation,  IPAC2023, Proc in IOP WEPM125 (2023)2024 J. Phys.: Conf. Ser. 2687 082039

Bernerd C. et al. Production of innovative radionuclides for medical applications at the CERN-MEDICIS facility. Ncul. Instr. Meth. B 542 (2023) 137-143. https://doi.org/10.1016/j.nimb.2023.05.008

Johnson, J.D., Heines, M., Bruchertseifer, F. et al. Resonant laser ionization and mass separation of 225Ac. Sci Rep 13, 1347 (2023). https://doi.org/10.1038

  • 2022

Vermeulen K., Van de Voorde M., Segers C., Coolkens A., Rodriguez Perez S., Daems N., Duchemin C., Crabbé M., Opsomer T., Saldarriaga Vargas C., Heinke R., Lambert L., Bernerd C., Burgoyne A.R., Cocolios, T.E., Stora T., Ooms M., Exploring the potential of high-molar activity Samarium-153 for  targeted radionuclide therapy with [153Sm]Sm-DOTA-TATE, Pharmaceutics-2012258, 10/2022.

Stora T. , Prior J.O. , Decristoforo C., Editorial on the Research Topic : MEDICIS-promed: Advances in radioactive ion beams for nuclear medicine, Fontiers in Medicine (2022) https://doi.org/10.3389/fmed.2022.1013619

Penescu L., Stora T., Stegemann S., Pitters J., Fiorina E., Dos Santos Augusto R., Schmitzer C., Wenander F., Parodi K., Ferrari A., Cocolios T. E., Technical Design Report for a Carbon-11 Treatment Facility, Frontiers in Medicine (2022) https://doi.org/10.3389/fmed.2021.697235

S.M. Collins, A.P. Robinson, P. Ivanov, U. Köster, T.E. Cocolios, B. Russell, B. Webster, A.J. Fenwick, C. Duchemin, J.P. Ramos, E. Chevallay, U. Jakobsson, S. Stegemann, P.H. Regan, T. Stora, Half-life determination of 155Tb from mass-separated samples produced at CERN-MEDICIS,Applied Radiation and Isotopes (2022) https://doi.org/10.1016/j.apradiso.2022.110480

  • 2021

Stegemann S et al. A porous hexagonal boron nitride powder compact for the production and release of radioactive 11C. Journal of the European Ceramic Society 41 (2021) 4086-4097.

Heinke R. et al. Efficient production of high specific activity Tm-167 at Paul Scherrer Institute and CERN-MEDICIS. Front Med (2021) Oct 12;8:712374 doi: 10.3389/fmed.2021.712374

Duchemin C., Cocolios T. E., Dockx K., Farooq-Smith G., Felden O., Formento-Cavaier R., Gebel R., Köster U., Neumaier B., Scholten B., Spahn I., Spellerberg S., Stamati N., Stegemann S., Verhoeven H. Production cross-section measurements of proton-induced reactions on natural tantalum in the 0.3 GeV to 1.7 GeV energy range. Applied Radiation and Isotopes (2021), https://doi.org/10.1016/j.apradiso.2021.109983

Martinez Palenzuela Y., Barozier V., Chevallay E., Cocolios T., Duchemin C., Fernier P., Huyse M., Lambert L., Lopez R., Marzari S., Ramos J.P., Stora T., Van Duppen P., Vorozhtsov A., The CERN-MEDICIS isotope separator beamline, Published in Frontiers in Medicine (2021), doi: 10.3389/fmed.2021.689281

Hurier S. MED-024 - ANSYS simulation for Ac-225 collections. https://cds.cern.ch/record/2767597

Duchemin C et al. on behalf of the MEDICIS collaboration, CERN-MEDICIS: a review since commissioning in 2017.  Frontiers in Medicine - Research Topic MEDICIS-Promed: Advances in Radioactive Ion Beams for Nuclear Medicine (2021) https://www.frontiersin.org/articles/10.3389/fmed.2021.693682/full

Duchemin C., Cocolios T. E., Dockx K., Farooq-Smith G., Felden O., Formento-Cavaier R., Gebel R., Köster U., Neumaier B., Scholten B., Spahn I., Spellerberg S., Stamati N., Stegemann S., Verhoeven H. Production cross-section measurements for terbium radionuclides of medical interest produced in tantalum targets irradiated by 0.3 GeV to 1.7 GeV protons and corresponding thick target yield calculations. Frontiers in Medicine (2021), doi: 10.3389/fmed.2021.625561

Van de Voorde M., Duchemin C., Heinke R., Lambert L., Chevallay E., Schneider T., Van Stenis M., Cocolios T.E., Cardinaels T., Ponsard B., Ooms M., Stora T., Burgoyne A., Production of Sm-153 with very high specific activity for targeted radionuclide therapy, Frontiers in Medicine (2021) https://doi.org/10.3389/fmed.2021.675221

Talip Z., Borgna F., Müller C., Ulrich J., Duchemin C., Ramos J.P., Stora T., Köster U., Nedjadi Y., Gadelshin V., Fedosseev V., Juget F., Bailat C., Frankhauser A., Wilkins S., Lambert L., Marsh B., Fedorov D., Chevallay E., Fernier P., Schibli R., Van Der Meulen N., Production of mass separated erbium-169 towards the first preclinical in vitro investigations. Frontiers in Medicine (2021), doi: 10.3389/fmed.2021.643175

Chevallay E, Duchemin C, Heinke R, Khalid U, Lambert L, Stora T. MEDICIS and MELISSA operation in 2020 during LS2. ISOLDE Newsletter (2021). 

D'Onofrio A., Gano L., Melo R., Mendes F., Oliveira M. C., Denoël T., Schaefer N., Viertl D., Fierle J., Coukos G., Dunn S., Prior J. O., Paulo A., "Biological evaluation of new TEM1 targeting recombinant antibodies for radioimmunotherapy: In vitro, in vivo and in silico studies" European Journal of Pharmaceutics and Biopharmaceutics, Vol. 8, 2021, 233-244.https://doi.org/10.1016/j.ejpb.2020.11.015.

D'Onofrio A.,Silva F., Gano L., Karczmarczyk U., Mikolajczak R., Garnuszek P., Paulo A., "Clickable Radiocomplexes with Trivalent Radiometals for Cancer Theranostics: In Vitro and in Vivo Studies" In review process Frontiers in Medicine - Research Topic MEDICIS-Promed: Advances in Radioactive Ion Beams for Nuclear Medicine (2021)

  • 2020

Duchemin C., Ramos J.P., Stora T., Aubert E., Audouin N., Barbero E., Barozier V., Bernardes A.P., Bertreix P., Boscher A., Burnel D., Catherall R., Cirilli M., Chevallay E., Cocolios T.E., Comte J., Crepieux B., Deschamps M., Dockx K., Dorsival A., Fedosseev V.N., Fernier P., Formento-Cavaier R., Gadelshin V.M., Gilardoni S., Grenard J.L., Haddad F., Heinke R., Juif B., Khan M., Köster U., Lambert L., Lilli G., Lunghi G., Marsh B.A., Martinez Palenzuela Y., Martins R., Marzari S., Menaa N., Michel N., Pozzi F., Riccardi F., Riegert J., Riggaz N., Rothe S., Stegemann S., Talip Z., Thiboud J., van der Meulen N.P., Vollaire J., Vuong N.T., Wendt K., Wilkins S., on behalf of the CERN-MEDICIS collaboration. CERN-MEDICIS: a unique facility for the production of non-conventional radionuclides for the medical research. Published in IPAC'20 JaCoW Proceedings (2020).

Cicone F, Denoël T, Gnesin S, Riggi N, Irving M, Jakka G, Schaefer N, Viertl, D, Coukos G, Prior JO. Preclinical Evaluation and Dosimetry of [(111)In]CHX-DTPA-scFv78-Fc Targeting Endosialin/Tumor Endothelial Marker 1 (TEM1). Mol Imaging Biol. 2020 Jan 28. doi: 10.1007/s11307-020-01479-8. Erratum in: Mol Imaging Biol. 2020 Mar 20;

Duchemin C, Heinke R, Lambert L, Ramos J.P, Stora T, Wilkins S. MEDICIS and MELISSA operation in 2019 during LS2. ISOLDE Newsletter (2020).

Formento-Cavaier R, Köster U, Crepieux B, Gadelshin V.M, Haddad F, Stora T, Wendt K. Very high specific activity erbium 169Er production for potential receptor-targeted therapy. NIMB Vol.463 (2020) 468-471. https://doi.org/10.1016/j.nimb.2019.04.022

Gadelshin V.M, Barozier V, Cocolios T.E, Fedoseev V.N, Formento-Cavaier R, Haddad F, Marsh B, Marzari S, Rothe S, Stora T, Studer D, Wendt K. MELISSA: Laser Ion Source setup at CERN-MEDICIS facility. NIMB Vol.463 (2020) 460-463. https://doi.org/10.1016/j.nimb.2019.04.024

Gadelshin V.M, Wilkins S. and the MEDICIS collaboration, First laser ions at the CERN-MEDICIS facility. Hyperfine interactions 241 (2020) Article number:55. https://doi.org/10.1007/s10751-020-01718-y

Stegemann S, Cocolios T.E, Dockx K, Leinders G, Popescu L, Ramos J.P, Rijpstra K, Stora T, Verwerft M, Vleugels J. NIMB Vol. 463 (2020) 403-407. https://doi.org/10.1016/j.nimb.2019.04.042

  • 2019

Cicone F, Gnesin S, Denoël T, Stora T, van der Meulen NP, Müller C, Vermeulen C, Benešová M, Köster U, Johnston K, Amato E, Auditore L, Coukos G, Stabin M, Schaefer N, Viertl D, Prior JO. Internal radiation dosimetry of a (152)Tb-labeled antibody in tumor-bearing mice. EJNMMI Res. 2019 Jun 11;9(1):53. doi:10.1186/s13550-019-0524-7

Gadelshin V, Heinke R, Kieck T, Kron T, Naubereit P, Rösch F, Stora T, Studer D, Wendt K. Measurement of the laser resonance ionization efficiency for lutetium. Radiochemica Acta Vol. 170, Issue 7. https://doi.org/10.1515/ract-2019-3118

Serikbayeva G, Separation device for molecular isotopes at MEDICIS. CERN-STUDENTS-Note-2019-039

  • 2018

Ruiz Quiros A. A chromatographic method to separate Sc(III) from Zn(II) ions: a step in the purification of 44Sc (an isotope of medical interest). CERN-STUDENTS-Note-2018-172

  • 2017

Cocolios T.E, Ferrari C, Reid F, Stora T. MEDICIS-Promed: an innovative training network for a new generation of professionals in nuclear medicine. In: Eskola H, Väïsänen O, Viik J,Hyttinen J. (eds) EMBEC & NBC 2017. EMBEC 2017, NBC 2017, IFMBE proceedings Vol.65. Springer, Singapour. https://link.springer.com/chapter/10.1007/978-981-10-5122-7_133#citeas

Formento-Cavaier R, Haddad F, Sounalet T, Stora T, Zahi I. Terbium radionuclides for theranostics applications: a focus on MEDICIS-Promed. Physics Procedia Vol.90 (2017) 157-163. https://doi.org/10.1016/j.phpro.2017.09.053

Gadelshin V, Cocolios T.E, Fedoseev V.N, Heinke R, Kieck T., Marsh B.A, Naubereit P, Rothe S, Stora T, Studer D, Van Duppen P, Wendt K. Hypefine Interactions 238 (2017) 28-34. https://link.springer.com/article/10.1007%2Fs10751-017-1406-x

  • 2016

Viertl D, Buchegger F, Prior J.O, Morel Ph, Ratib O, Buhler L, Stora T. MEDICIS-Promed: Medicis-produced radioisotope beams for medicine - an innovative training network. https://www.thegreenjournal.com/article/S0167-8140(16)30178-5/pdf

  • 2014

Dos Santos Augusto R.M, Buehler L, Lawson Z, Marzari S, Stachura M, Stora T, and the CERN-MEDICIS collaboration, CERN-MEDICIS(MEDical Isotopes Collected from ISolde): a new facility. Applied Sciences Vol.4 Issue 2 (2014) 265-281. doi: 10.3390/app4020265